Evolutionary Neuroscience

(Director, Chet Sherwood). The Laboratory for Evolutionary Neuroanatomy is dedicated to research on the evolution of brain structure in primates and other mammals. The lab’s research combines neuroscience, behavioral science, and evolutionary biology to investigate how species differences in brain anatomy relate to sensorimotor and cognitive adaptations. Current studies are aimed at examining the molecular and celllular architecture of the modern human cerebral cortex in comparison with our close living relatives, the great apes.

Major equipment: Zeiss Axioplan 2 microscope equipped for fluorescence, brightfield, and polarized light; MBF Bioscience integrated stereology and neuron reconstruction analysis software; Agilent Stratagene Mx3005p qPCR system; Equipment for histological sectioning, immunocytochemical staining, and Western blotting.

Sample publication: C.C. Sherwood, M.A. Raghanti, C.D. Stimpson, M.A. Spocter, M. Uddin, A.M. Boddy, D.E. Wildman, C.J. Bonar, A.H. Lewandowski, K.A. Phillips, J.M. Erwin, and P.R. Hof (2010) Inhibitory interneurons of the human prefrontal cortex display conserved evolution of the phenotype and related genes. Proc. R. Soc. B. 277: 101-120.

Link to the lab’s website

Posted in Uncategorized, August 24th, 2010